Farreras Medicina Interna Pdf Download LINK


Farreras Medicina Interna Pdf Download

given the rapid pace of change in cuba and the availability of new knowledge and technologies, it is possible that the burden of disease will change over time, and the etiology of cirrhosis will change. future studies should be conducted to establish whether the trends are consistent with international forecasts and to identify the factors that can be targeted to reduce mortality in the short and long terms.

cirrhosis is a disease of the liver and the most common cause of end-stage liver disease. worldwide, it is the 12th leading cause of death and the third leading cause of liver cancer.[11. gins p, arroyo v. cirrosis heptica. in: farreras r, editor.

according to the most recent data (2015) from the international agency for research on cancer, in the western pacific region, 55,473 cases of lc occurred in 2013, with mortality rates ranging from 1.8 per 100,000 in new zealand to 0.6 per 100,000 in australia. the highest mortality rate for lc was in india and china (7.1 per 100,000).[2121. world health organization regional office for the western pacific. cancer fact sheet: global cancer statistics. version 1.6. 2014 [cited 2020 mar 31]; available at: 2222. gbd 2015 cancer collaborators. the global, regional, and national burden of cancer in 195 countries, 19902015: a systematic analysis for the global burden of disease study 2015. lancet. 2016;387(10029):1881-96. available at:

un documento de referncia comprendiene una revisin ngeolgica, anatomana patolgica y clnica, y su caracterizacion; asimismo se presentan una recopilacion ngeografica y epidemiolgica, y una seccion de tratamiento y profilaxis.
the hr for women (1.46; 95% confidence interval [ci], 1.37-1.56) was similar to that for men, even though no data were available for death rates in women in the subgroup analysis. alcohol is a major risk factor associated with lc, but little is known about the impact of this factor on mortality in women. this result is unexpected, because women are more likely than men to develop cirrhosis after heavy alcohol consumption and, therefore, should have higher rates of disease. however, the impact of this difference could be overshadowed by the other risk factors, such as hepatitis c virus, and non-alcoholic liver diseases such as non-alcoholic fatty liver disease. furthermore, being a woman generally implies a lower socioeconomic status and a higher risk of unemployment, which in turn may imply poor access to health services and to prevention and screening programs.[2828. ezzati m, sell m, gunnell d. inequalities in alcohol-related death: an overview. epidemiologic reviews. 2006 nov [cited 2020 mar 31];28(4):338-45. available at:
it is important to stress that these factors and the risk of death by cirrhosis attributable to them are common to all countries and are not associated with any other factors or region. in canada, the highest hr was associated with being a woman and the lowest with diabetes, suggesting that policies to reduce this impact should focus on screening women for both lc and diabetes. one of the public health interventions in this scenario should be aimed at reducing the consumption of alcohol in women and adolescents (particularly in the population with a higher risk of lc).